Conolidine’s analgesic effects stem from its conversation with non-opioid pain pathways. Contrary to opioids, which bind to µ-opioid receptors within the central nervous system, conolidine modulates alternate molecular targets. A Science Advances research discovered that conolidine interacts With all the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availabil... https://caidenybcbx.idblogz.com/39161097/alternative-natural-pain-relief-to-replace-traditional-painkillers-secrets